In some cases, the concentrations may increase (increasing the risk of side effects) and, in others, drop (decreasing the effectiveness of the drug). Milk thistle can change the way that your body metabolizes certain drugs in the liver, triggering interactions with: Supplements that may interact with these medications include fish oil and St. John's wort. The study is created by eHealthMe based on reports of 236 people who take Lisinopril and Milk thistle from the FDA, and is updated regularly. Select a subject to preview related courses: In doing your research into the safety of milk thistle you learn that the U.S. Food and Drug Administration (FDA) does not strictly regulate herbs and supplements. Answered by Dr. Anne Larson: No Interaction: These medicines do not interact with Milk Thistle… There are no regulated manufacturing standards in place for many herbal compounds and some marketed supplements have been found to be contaminated with toxic metals or other drugs. You would probably think that they are at the very least stretching the truth, but it might surprise you to learn that there is such a medicine. flashcard set{{course.flashcardSetCoun > 1 ? Drug Interactions . Learn about supplement interactions with apixaban (Eliquis), rivaroxaban (Xarelto) and other blood thinner drugs in the direct factor Xa inhibitors class. Did you know… We have over 220 college You can test out of the A warning about milk thistle (silymarin) and drug interactions. advertisements are served by third party advertising companies. S Wanwimolruk , V Prachayasittikul, “Cytochrome P450 enzyme mediated herbal drug interactions (Part 1)”, EXCLI J. Hi. The LIVESTRONG Foundation and LIVESTRONG.COM do not endorse Visit the Introduction to Pharmacology page to learn more. Milk thistle may reduce your blood sugar, so it needs to be used with caution as it may trigger hypoglycemia (low blood sugar) in people on diabetes medications. Take milk thistle in capsule, extract or infusion form. Pregnancy or breastfeeding. The milk thistle I have is 1000mg. Raloxifene ( Evista) Interaction Rating: Moderate Be cautious with this combination.Talk with your health provider. Below is a short list of some other medications that are processed through the CYP3A4 enzyme. You think it might be helpful for your gallbladder issues. Benefits A herbal blend that maintains liver health. Clinical evidence. Cancer - Some early studies suggest that milk thistle may stop cancer cells from dividing and reduce blood supply to tumors. It is native to Mediterranean countries. Milk, Soy Milk, Milk-Based Smoothies Calcium can interfere with the effectiveness of thyroid medication. * MILK THISTLE. USES: Milk thistle has been used for diabetes in combination with standard treatment. Summary: Drug interactions are reported among people who take Lisinopril and Milk thistle. Blood pressure is defined as the pressure pushed against artery walls as a result of the heart pumping blood. All other trademarks and copyrights are the property of their respective owners. As far as I know there have never been any serious negative side effects attributable to Milk Thistle. While no scientific evidence exists to determine the entire effect milk thistle has on blood pressure, it may be possible this herb may indirectly lower blood pressure. - Causes, Symptoms & Treatment, What Is Dysphagia? Good luck. The seeds of the milk thistle plant are commonly used to protect the liver from damage caused by hepatitis viruses as well as alcohol and other substances. Although milk thistle helps reduce glucose levels in the blood, meaning that it may be beneficial for patients with diabetes, it is very important to understand that if medication for this … Prior to starting a supplementation routine with milk thistle, discuss the safety and dosage requirements with your physician. Taking milk thistle might affect this enzyme and drugs it processes, such as diazepam (Valium), warfarin (Coumadin, Jantoven) and others. Some cellular studies found that milk thistle may affect CYP enzymes in the liver that metabolize drugs; human studies suggest this effect is minor, but interactions are possible [ 29 ]. The National Diabetes Information Clearinghouse reports high blood sugar contributes to high blood pressure. Milk thistle may also help patients with Hepatitis C. Mushroom Poisoning -Animal studies have found that milk thistle counteracts toxic effects of the ''death cap'' mushroom (. Some people also call it Mary thistle and holy thistle. The University of Maryland Medical Center reports these compounds are responsible for enhancing liver cell reproduction, and protecting new liver cells from damage. This investigation will take approximately 8 weeks and involve 10 clinic visits. 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